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NIDO, AMOP and vWD domains of MUC4 play synergic role in MUC4 mediated signaling

MUC4 mucin is well known as an important potential target to overcome pancreatic cancer. Three unique domains (NIDO, AMOP, and vWD) with unclear roles only present in MUC4 but are not found in other membrane-bound mucins. Our previous studies first reported that its splice variant, MUC4/Y can be a m...

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Detalles Bibliográficos
Autores principales: Zhu, Yi, Zhang, Jing-Jing, Peng, Yun-Peng, Liu, Xian, Xie, Kun-Ling, Tang, Jie, Jiang, Kui-Rong, Gao, Wen-Tao, Tian, Lei, Zhang, Kai, Xu, Ze-Kuan, Miao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354666/
https://www.ncbi.nlm.nih.gov/pubmed/28060749
http://dx.doi.org/10.18632/oncotarget.14420