Lovastatin upregulates microRNA-29b to reduce oxidative stress in rats with multiple cardiovascular risk factors

AIMS: Proteasome-linked oxidative stress is believed to cause endothelial dysfunction, an early event in cardiovascular diseases (CVD). Statin, as HMG-CoA reductase inhibitor, prevents endothelial dysfunction in CVD. However, the molecular mechanism of statin-mediated normalization of endothelial fu...

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Detalles Bibliográficos
Autores principales: Wang, Fu, Ma, Hui, Liang, Wen-Jing, Yang, Jing-Jing, Wang, Xue-Qing, Shan, Mei-Rong, Chen, Yuan, Jia, Min, Yin, Ya-Ling, Sun, Xue-Ying, Zhang, Jia-Ning, Peng, Qi-Sheng, Chen, Yu-Guo, Liu, Li-Ying, Li, Peng, Guo, Tao, Wang, Shuang-Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354712/
https://www.ncbi.nlm.nih.gov/pubmed/28061433
http://dx.doi.org/10.18632/oncotarget.14462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354712/
https://www.ncbi.nlm.nih.gov/pubmed/28061433
http://dx.doi.org/10.18632/oncotarget.14462

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