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Lovastatin upregulates microRNA-29b to reduce oxidative stress in rats with multiple cardiovascular risk factors
AIMS: Proteasome-linked oxidative stress is believed to cause endothelial dysfunction, an early event in cardiovascular diseases (CVD). Statin, as HMG-CoA reductase inhibitor, prevents endothelial dysfunction in CVD. However, the molecular mechanism of statin-mediated normalization of endothelial fu...
Autores principales: | Wang, Fu, Ma, Hui, Liang, Wen-Jing, Yang, Jing-Jing, Wang, Xue-Qing, Shan, Mei-Rong, Chen, Yuan, Jia, Min, Yin, Ya-Ling, Sun, Xue-Ying, Zhang, Jia-Ning, Peng, Qi-Sheng, Chen, Yu-Guo, Liu, Li-Ying, Li, Peng, Guo, Tao, Wang, Shuang-Xi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354712/ https://www.ncbi.nlm.nih.gov/pubmed/28061433 http://dx.doi.org/10.18632/oncotarget.14462 |
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