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Targeting the pro-angiogenic forms of VEGF or inhibiting their expression as anti-cancer strategies

Tumor growth relies on oxygen and blood supply depending on neo-vascularization. This process is mediated by the Vascular Endothelial Growth Factor (VEGF) in many tumors. This paradigm has led to the development of specific therapeutic approaches targeting VEGF or its receptors. Despite their promis...

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Detalles Bibliográficos
Autores principales: Guyot, Mélanie, Hilmi, Caroline, Ambrosetti, Damien, Merlano, Marco, Nigro, Cristiana Lo, Durivault, Jérôme, Grépin, Renaud, Pagès, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354723/
https://www.ncbi.nlm.nih.gov/pubmed/27999187
http://dx.doi.org/10.18632/oncotarget.13942