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Targeting the pro-angiogenic forms of VEGF or inhibiting their expression as anti-cancer strategies
Tumor growth relies on oxygen and blood supply depending on neo-vascularization. This process is mediated by the Vascular Endothelial Growth Factor (VEGF) in many tumors. This paradigm has led to the development of specific therapeutic approaches targeting VEGF or its receptors. Despite their promis...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354723/ https://www.ncbi.nlm.nih.gov/pubmed/27999187 http://dx.doi.org/10.18632/oncotarget.13942 |