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MutY-Homolog (MYH) inhibition reduces pancreatic cancer cell growth and increases chemosensitivity

Patients with pancreatic ductal adenocarcinoma (PC) have a poor prognosis due to metastases and chemoresistance. PC is characterized by extensive fibrosis, which creates a hypoxic microenvironment, and leads to increased chemoresistance and intracellular oxidative stress. Thus, proteins that protect...

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Detalles Bibliográficos
Autores principales: Sharbeen, George, Youkhana, Janet, Mawson, Amanda, McCarroll, Joshua, Nunez, Andrea, Biankin, Andrew, Johns, Amber, Goldstein, David, Phillips, Phoebe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354726/
https://www.ncbi.nlm.nih.gov/pubmed/27999205
http://dx.doi.org/10.18632/oncotarget.13985