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MutY-Homolog (MYH) inhibition reduces pancreatic cancer cell growth and increases chemosensitivity
Patients with pancreatic ductal adenocarcinoma (PC) have a poor prognosis due to metastases and chemoresistance. PC is characterized by extensive fibrosis, which creates a hypoxic microenvironment, and leads to increased chemoresistance and intracellular oxidative stress. Thus, proteins that protect...
Autores principales: | Sharbeen, George, Youkhana, Janet, Mawson, Amanda, McCarroll, Joshua, Nunez, Andrea, Biankin, Andrew, Johns, Amber, Goldstein, David, Phillips, Phoebe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354726/ https://www.ncbi.nlm.nih.gov/pubmed/27999205 http://dx.doi.org/10.18632/oncotarget.13985 |
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