Antagonizing functions of BARD1 and its alternatively spliced variant BARD1δ in telomere stability

Previous reports have shown that expression of BARD1δ, a deletion-bearing isoform of BARD1, correlates with tumor aggressiveness and progression. We show that expression of BARD1δ induces cell cycle arrest in vitro and in vivo in non-malignant cells. We investigated the mechanism that leads to proli...

Descripción completa

Detalles Bibliográficos
Autores principales: Pilyugin, Maxim, André, Pierre-Alain, Ratajska, Magdalena, Kuzniacka, Alina, Limon, Janusz, Tournier, Benjamin B., Colas, Julien, Laurent, Geoff, Irminger-Finger, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354735/
https://www.ncbi.nlm.nih.gov/pubmed/28030839
http://dx.doi.org/10.18632/oncotarget.14068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354735/
https://www.ncbi.nlm.nih.gov/pubmed/28030839
http://dx.doi.org/10.18632/oncotarget.14068

Ejemplares similares