Targeted delivery of CRISPR/Cas9 to prostate cancer by modified gRNA using a flexible aptamer-cationic liposome

The potent ability of CRISPR/Cas9 system to inhibit the expression of targeted gene is being exploited as a new class of therapeutics for a variety of diseases. However, the efficient and safe delivery of CRISPR/Cas9 into specific cell populations is still the principal challenge in the clinical dev...

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Detalles Bibliográficos
Autores principales: Zhen, Shuai, Takahashi, Yoichiro, Narita, Shunichi, Yang, Yi-Chen, Li, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354738/
https://www.ncbi.nlm.nih.gov/pubmed/28030843
http://dx.doi.org/10.18632/oncotarget.14072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354738/
https://www.ncbi.nlm.nih.gov/pubmed/28030843
http://dx.doi.org/10.18632/oncotarget.14072

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