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Overendocytosis of superparamagnetic iron oxide particles increases apoptosis and triggers autophagic cell death in human osteosarcoma cell under a spinning magnetic field

The toxicity of superparamagnetic iron oxide nanoparticles (SPIONs) is still a vital topic of debate and the mechanisms remain unclear. In the present study, overdose SPIONs could induce osteosarcoma cell death and the effects were exaggerated when combined with spinning magnetic field (SMF). In the...

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Detalles Bibliográficos
Autores principales: Du, Shaohua, Li, Jingxiong, Du, Chonghua, Huang, Zhongming, Chen, Guangnan, Yan, Weiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354741/
https://www.ncbi.nlm.nih.gov/pubmed/28031531
http://dx.doi.org/10.18632/oncotarget.14114