V-ATPase inhibition increases cancer cell stiffness and blocks membrane related Ras signaling - a new option for HCC therapy

Hepatocellular carcinoma (HCC) is the fifth most frequent cancer worldwide and the third leading cause of cancer-related death. However, therapy options are limited leaving an urgent need to develop new strategies. Currently, targeting cancer cell lipid and cholesterol metabolism is gaining interest...

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Detalles Bibliográficos
Autores principales: Bartel, Karin, Winzi, Maria, Ulrich, Melanie, Koeberle, Andreas, Menche, Dirk, Werz, Oliver, Müller, Rolf, Guck, Jochen, Vollmar, Angelika M., von Schwarzenberg, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354746/
https://www.ncbi.nlm.nih.gov/pubmed/28036299
http://dx.doi.org/10.18632/oncotarget.14339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354746/
https://www.ncbi.nlm.nih.gov/pubmed/28036299
http://dx.doi.org/10.18632/oncotarget.14339

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