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HIF-1α induces the epithelial-mesenchymal transition in gastric cancer stem cells through the Snail pathway

Substantial evidence suggests that the epithelial-mesenchymal transition (EMT) phenotype is associated with the invasive characteristics of cancer stem cells (CSCs),which possess an EMT phenotype that may predominate in tumor invasion and metastasis. However, the mechanisms for the generation and re...

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Detalles Bibliográficos
Autores principales: Yang, Shi-wei, Zhang, Zhi-gang, Hao, Ying-xue, Zhao, Yong-liang, Qian, Feng, Shi, Yan, Li, Ping-ang, Liu, Chun-yang, Yu, Pei-wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354751/
https://www.ncbi.nlm.nih.gov/pubmed/28076840
http://dx.doi.org/10.18632/oncotarget.14484