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EGF induces epithelial-mesenchymal transition and cancer stem-like cell properties in human oral cancer cells via promoting Warburg effect

“Warburg effect”, the enhanced glycolysis or aerobic glycolysis, confers cancer cells the ability to survive and proliferate even under stressed conditions. In this study, we explored the role of epidermal growth factor (EGF) in orchestrating Warburg effect, the epithelial-mesenchymal transition (EM...

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Detalles Bibliográficos
Autores principales: Xu, Qilin, Zhang, Qunzhou, Ishida, Yasutaka, Hajjar, Souren, Tang, Xudong, Shi, Haoran, Dang, Chi V., Le, Anh D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354753/
https://www.ncbi.nlm.nih.gov/pubmed/27926487
http://dx.doi.org/10.18632/oncotarget.13771