Inhibition of long non-coding RNA UCA1 by CRISPR/Cas9 attenuated malignant phenotypes of bladder cancer

CRISPR/Cas9 is a novel and effective genome editing technique, but its application is not widely expanded to manipulate long non-coding RNA (lncRNA) expression. The lncRNA urothelial carcinoma-associated 1 (UCA1) is upregulated in bladder cancer and promotes the progression of bladder cancer. Here,...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhen, Shuai, Hua, Ling, Liu, Yun-Hui, Sun, Xiao-Min, Jiang, Meng-Meng, Chen, Wei, Zhao, Le, Li, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354759/
https://www.ncbi.nlm.nih.gov/pubmed/28038452
http://dx.doi.org/10.18632/oncotarget.14176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354759/
https://www.ncbi.nlm.nih.gov/pubmed/28038452
http://dx.doi.org/10.18632/oncotarget.14176

Ejemplares similares