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Inhibition of long non-coding RNA UCA1 by CRISPR/Cas9 attenuated malignant phenotypes of bladder cancer

CRISPR/Cas9 is a novel and effective genome editing technique, but its application is not widely expanded to manipulate long non-coding RNA (lncRNA) expression. The lncRNA urothelial carcinoma-associated 1 (UCA1) is upregulated in bladder cancer and promotes the progression of bladder cancer. Here,...

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Detalles Bibliográficos
Autores principales:	Zhen, Shuai, Hua, Ling, Liu, Yun-Hui, Sun, Xiao-Min, Jiang, Meng-Meng, Chen, Wei, Zhao, Le, Li, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354759/ https://www.ncbi.nlm.nih.gov/pubmed/28038452 http://dx.doi.org/10.18632/oncotarget.14176

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