Melatonin protects against arsenic trioxide-induced liver injury by the upregulation of Nrf2 expression through the activation of PI3K/AKT pathway

Melatonin has been demonstrated to have anti-inflammatory and antioxidant effects. The aim of this study was to investigate the protective effects of melatonin on arsenic trioxide (As(2)O(3))-induced toxicity in liver and oxidative stress in rats. The rats were injected with 3mg/kg As(2)O(3) on alte...

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Detalles Bibliográficos
Autores principales: Zhang, Yue, Wei, Zhengkai, Liu, Weijian, Wang, Jingjing, He, Xuexiu, Huang, Hailong, Zhang, Jiali, Yang, Zhengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354794/
https://www.ncbi.nlm.nih.gov/pubmed/27980225
http://dx.doi.org/10.18632/oncotarget.13931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354794/
https://www.ncbi.nlm.nih.gov/pubmed/27980225
http://dx.doi.org/10.18632/oncotarget.13931

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