The JAZF1-SUZ12 fusion protein disrupts PRC2 complexes and impairs chromatin repression during human endometrial stromal tumorogenesis

The Polycomb repressive complex 2 (PRC2), which contains three core proteins EZH2, EED and SUZ12, controls chromatin compaction and transcription repression through trimethylation of lysine 27 on histone 3. The (7;17)(p15;q21) chromosomal translocation present in most cases of endometrial stromal sa...

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Detalles Bibliográficos
Autores principales: Ma, Xianyong, Wang, Jinglan, Wang, Jianhui, Ma, Charles X., Gao, Xiaobin, Patriub, Vytas, Sklar, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354813/
https://www.ncbi.nlm.nih.gov/pubmed/27845897
http://dx.doi.org/10.18632/oncotarget.13270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354813/
https://www.ncbi.nlm.nih.gov/pubmed/27845897
http://dx.doi.org/10.18632/oncotarget.13270

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