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Antitumor effect of combination of the inhibitors of two new oncotargets: proton pumps and reverse transcriptase

Tumor therapy needs new approaches in order to improve efficacy and reduce toxicity of the current treatments. The acidic microenvironment and the expression of high levels of endogenous non-telomerase reverse transcriptase (RT) are common features of malignant tumor cells. The anti-acidic proton pu...

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Detalles Bibliográficos
Autores principales: Lugini, Luana, Sciamanna, Ilaria, Federici, Cristina, Iessi, Elisabetta, Spugnini, Enrico Pierluigi, Fais, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354819/
https://www.ncbi.nlm.nih.gov/pubmed/27926505
http://dx.doi.org/10.18632/oncotarget.13792