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Antitumor effect of combination of the inhibitors of two new oncotargets: proton pumps and reverse transcriptase
Tumor therapy needs new approaches in order to improve efficacy and reduce toxicity of the current treatments. The acidic microenvironment and the expression of high levels of endogenous non-telomerase reverse transcriptase (RT) are common features of malignant tumor cells. The anti-acidic proton pu...
Autores principales: | Lugini, Luana, Sciamanna, Ilaria, Federici, Cristina, Iessi, Elisabetta, Spugnini, Enrico Pierluigi, Fais, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354819/ https://www.ncbi.nlm.nih.gov/pubmed/27926505 http://dx.doi.org/10.18632/oncotarget.13792 |
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