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Decline in arylsulfatase B leads to increased invasiveness of melanoma cells

Arylsulfatase B (ARSB; N-acetylgalactosamine 4-sulfatase) is reduced in several malignancies, but levels in melanoma have not been investigated previously. Experiments were performed in melanoma cell lines to determine ARSB activity and impact on melanoma invasiveness. ARSB activity was reduced ~50%...

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Detalles Bibliográficos
Autores principales: Bhattacharyya, Sumit, Feferman, Leo, Terai, Kaoru, Dudek, Arkadiusz Z., Tobacman, Joanne K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354821/
https://www.ncbi.nlm.nih.gov/pubmed/27926479
http://dx.doi.org/10.18632/oncotarget.13751