Cargando…
The pre-existing population of 5S rRNA effects p53 stabilization during ribosome biogenesis inhibition
Pre-ribosomal complex RPL5/RPL11/5S rRNA (5S RNP) is considered the central MDM2 inhibitory complex that control p53 stabilization during ribosome biogenesis inhibition. Despite its role is well defined, the dynamic of 5S RNP assembly still requires further characterization. In the present work, we...
Autores principales: | Onofrillo, Carmine, Galbiati, Alice, Montanaro, Lorenzo, Derenzini, Massimo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354829/ https://www.ncbi.nlm.nih.gov/pubmed/28032591 http://dx.doi.org/10.18632/oncotarget.13833 |
Ejemplares similares
-
Therapeutic dosages of aspirin counteract the IL-6 induced pro-tumorigenic effects by slowing down the ribosome biogenesis rate
por: Brighenti, Elisa, et al.
Publicado: (2016) -
The Ribosome Biogenesis—Cancer Connection
por: Penzo, Marianna, et al.
Publicado: (2019) -
Turning Uridines around: Role of rRNA Pseudouridylation in Ribosome Biogenesis and Ribosomal Function
por: Penzo, Marianna, et al.
Publicado: (2018) -
Inhibition of Human Dyskerin as a New Approach to Target Ribosome Biogenesis
por: Rocchi, Laura, et al.
Publicado: (2014) -
Epigenetic up-regulation of ribosome biogenesis and more aggressive phenotype triggered by the lack of the histone demethylase JHDM1B in mammary epithelial cells
por: Galbiati, Alice, et al.
Publicado: (2017)