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Structurally related odorant ligands of the olfactory receptor OR51E2 differentially promote metastasis emergence and tumor growth

Olfactory receptors are G protein-coupled receptors. Some of them are expressed in tumor cells, such as the OR51E2 receptor overexpressed in LNCaP prostate cancer cells. It is considered a prostate tumor marker. We previously demonstrated that this receptor is able to promote LNCaP cell invasiveness...

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Detalles Bibliográficos
Autores principales: Sanz, Guenhaël, Leray, Isabelle, Grébert, Denise, Antoine, Sharmilee, Acquistapace, Adrien, Muscat, Adeline, Boukadiri, Abdelhak, Mir, Lluis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354835/
https://www.ncbi.nlm.nih.gov/pubmed/28032594
http://dx.doi.org/10.18632/oncotarget.13836