Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation

Lung cancer is a deadly disease with increasing cases diagnosed worldwide and still a very poor prognosis. While mutations in the retinoblastoma (RB1) tumor suppressor have been reported in lung cancer, mainly in small cell lung carcinoma, the tumor suppressive role of its relatives p107 and p130 is...

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Detalles Bibliográficos
Autores principales: Lázaro, Sara, Pérez-Crespo, Miriam, Enguita, Ana Belén, Hernández, Pilar, Martínez-Palacio, Jesús, Oteo, Marta, Sage, Julien, Paramio, Jesús M., Santos, Mirentxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354839/
https://www.ncbi.nlm.nih.gov/pubmed/27966456
http://dx.doi.org/10.18632/oncotarget.13875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354839/
https://www.ncbi.nlm.nih.gov/pubmed/27966456
http://dx.doi.org/10.18632/oncotarget.13875

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