GABARAPL1 suppresses metastasis by counteracting PI3K/Akt pathway in prostate cancer

Metastasis remains the primary cause of prostate cancer (CaP)-related death. Using a genome wide shRNA screen, we identified GABARAPL1 as a potential CaP metastasis suppressor. GABARAPL1 mRNA levels inversely correlate with the invasive potential of a panel of human CaP cell lines. Lower mRNA levels...

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Detalles Bibliográficos
Autores principales: Su, Wei, Li, Shibao, Chen, Xiaofan, Yin, Lingyu, Ma, Ping, Ma, Yingyu, Su, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354845/
https://www.ncbi.nlm.nih.gov/pubmed/27966458
http://dx.doi.org/10.18632/oncotarget.13879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354845/
https://www.ncbi.nlm.nih.gov/pubmed/27966458
http://dx.doi.org/10.18632/oncotarget.13879

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