Potent CD4(+) T cell-associated antitumor memory responses induced by trifunctional bispecific antibodies in combination with immune checkpoint inhibition

Combinatorial approaches of immunotherapy hold great promise for the treatment of malignant disease. Here, we examined the potential of combining an immune checkpoint inhibitor and trifunctional bispecific antibodies (trAbs) in a preclinical melanoma mouse model using surrogate antibodies of Ipilimu...

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Detalles Bibliográficos
Autores principales: Deppisch, Nina, Ruf, Peter, Eißler, Nina, Lindhofer, Horst, Mocikat, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354850/
https://www.ncbi.nlm.nih.gov/pubmed/27966460
http://dx.doi.org/10.18632/oncotarget.13888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354850/
https://www.ncbi.nlm.nih.gov/pubmed/27966460
http://dx.doi.org/10.18632/oncotarget.13888

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