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The miR-196b miRNA inhibits the GATA6 intestinal transcription factor and is upregulated in colon cancer patients

OBJECTIVE: To explore the possible misexpression of the microRNA miR-196b in colorectal cancer (CRC) and its role in controlling the expression of GATA6, a putative target gene crucial to intestinal cell homeostasis and tumorigenesis. DESIGN: The expression of miR-196b was analysed by qRT-PCR in sur...

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Detalles Bibliográficos
Autores principales: Fantini, Sebastian, Salsi, Valentina, Reggiani, Luca, Maiorana, Antonino, Zappavigna, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354868/
https://www.ncbi.nlm.nih.gov/pubmed/27902469
http://dx.doi.org/10.18632/oncotarget.13580