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The miR-196b miRNA inhibits the GATA6 intestinal transcription factor and is upregulated in colon cancer patients
OBJECTIVE: To explore the possible misexpression of the microRNA miR-196b in colorectal cancer (CRC) and its role in controlling the expression of GATA6, a putative target gene crucial to intestinal cell homeostasis and tumorigenesis. DESIGN: The expression of miR-196b was analysed by qRT-PCR in sur...
Autores principales: | Fantini, Sebastian, Salsi, Valentina, Reggiani, Luca, Maiorana, Antonino, Zappavigna, Vincenzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354868/ https://www.ncbi.nlm.nih.gov/pubmed/27902469 http://dx.doi.org/10.18632/oncotarget.13580 |
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