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Knockdown of RNF2 induces cell cycle arrest and apoptosis in prostate cancer cells through the upregulation of TXNIP

RNF2, also known as RING1b or RING2, is identified as the catalytic subunit of polycomb repressive complex 1 (PRC1), which mediates the mono-ubiquitination of histone H2A. RNF2 has been proved to have oncogenic function in many kinds of cancers, but the function of RNF2 in prostate cancer (PCa) has...

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Detalles Bibliográficos
Autores principales: Wei, Ming, Jiao, Dian, Han, Donghui, Wu, Jieheng, Wei, Feilong, Zheng, Guoxu, Guo, Zhangyan, Xi, Wenjin, Yang, Fa, Xie, Pin, Zhang, Lingling, Yang, An-Gang, Wang, He, Qin, Weijun, Wen, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354911/
https://www.ncbi.nlm.nih.gov/pubmed/28029659
http://dx.doi.org/10.18632/oncotarget.14142