Epstein-Barr virus EBNA2 directs doxorubicin resistance of B cell lymphoma through CCL3 and CCL4-mediated activation of NF-κB and Btk

Epstein-Barr virus (EBV)-encoded nuclear antigen, EBNA2, expressed in EBV-infected B lymphocytes is critical for lymphoblastoid cell growth. Microarray profiling and cytokine array screening revealed that EBNA2 is associated with upregulation of the chemokines CCL3 and CCL4 in lymphoma cells. Deplet...

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Detalles Bibliográficos
Autores principales: Kim, Joo Hyun, Kim, Won Seog, Hong, Jung Yong, Ryu, Kung Ju, Kim, Seok Jin, Park, Chaehwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354914/
https://www.ncbi.nlm.nih.gov/pubmed/28036258
http://dx.doi.org/10.18632/oncotarget.14243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354914/
https://www.ncbi.nlm.nih.gov/pubmed/28036258
http://dx.doi.org/10.18632/oncotarget.14243

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