Nerve growth factor-induced Akt/mTOR activation protects the ischemic heart via restoring autophagic flux and attenuating ubiquitinated protein accumulation

The dysregulation of autophagy is related to a variety of cardiovascular diseases, such as myocardial ischemia/reperfusion (I/R). Nerve growth factor (NGF) has been shown to have therapeutic potential in ischaemic heart injury. In this study, we demonstrate that NGF administration can accelerate aut...

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Detalles Bibliográficos
Autores principales: Wang, Zhou-Guang, Li, Hao, Huang, Yan, Li, Rui, Wang, Xiao-Fan, Yu, Li-Xia, Guang, Xue-Qiang, Li, Lei, Zhang, Hong-Yu, Zhao, Ying-Zheng, Zhang, Chunxiang, Li, Xiao-Kun, Wu, Rong-Zhou, Chu, Mao-Ping, Xiao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354918/
https://www.ncbi.nlm.nih.gov/pubmed/28036273
http://dx.doi.org/10.18632/oncotarget.14284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354918/
https://www.ncbi.nlm.nih.gov/pubmed/28036273
http://dx.doi.org/10.18632/oncotarget.14284

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