Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer

Hormone therapy targeting estrogen receptor (ER) is the principal treatment for ER-positive breast cancers. However, many cancers develop resistance to hormone therapy while retaining ER expression. Identifying new druggable mediators of ER function can help to increase the efficacy of ER-targeting...

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Detalles Bibliográficos
Autores principales: McDermott, Martina S.J., Chumanevich, Alexander A., Lim, Chang-uk, Liang, Jiaxin, Chen, Mengqian, Altilia, Serena, Oliver, David, Rae, James M., Shtutman, Michael, Kiaris, Hippokratis, Győrffy, Balázs, Roninson, Igor B., Broude, Eugenia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355036/
https://www.ncbi.nlm.nih.gov/pubmed/28147342
http://dx.doi.org/10.18632/oncotarget.14894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355036/
https://www.ncbi.nlm.nih.gov/pubmed/28147342
http://dx.doi.org/10.18632/oncotarget.14894

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