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Analysis of acquired mutations in transgenes arising in Ba/F3 transformation assays: findings and recommendations

The identification and functional validation of potentially oncogenic mutations in leukemia is an essential step toward a future of personalized targeted therapy. To assess the oncogenic capacity of individual mutations, reliable and scalable in vitro experimental approaches are required. Since 1988...

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Detalles Bibliográficos
Autores principales: Watanabe-Smith, Kevin, Godil, Jamila, Agarwal, Anupriya, Tognon, Cristina, Druker, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355038/
https://www.ncbi.nlm.nih.gov/pubmed/28208123
http://dx.doi.org/10.18632/oncotarget.15392