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Analysis of acquired mutations in transgenes arising in Ba/F3 transformation assays: findings and recommendations
The identification and functional validation of potentially oncogenic mutations in leukemia is an essential step toward a future of personalized targeted therapy. To assess the oncogenic capacity of individual mutations, reliable and scalable in vitro experimental approaches are required. Since 1988...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355038/ https://www.ncbi.nlm.nih.gov/pubmed/28208123 http://dx.doi.org/10.18632/oncotarget.15392 |