Cargando…

Mitotic catastrophe and cell cycle arrest are alternative cell death pathways executed by bortezomib in rituximab resistant B-cell lymphoma cells

The ubiqutin-proteasome system (UPS) plays a role in rituximab-chemotherapy resistance and bortezomib (BTZ) possesses caspase-dependent (i.e. Bak stabilization) and a less characterized caspase–independent mechanism-of-action(s). Here, we define BTZ-induced caspase-independent cell death pathways. A...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Juan J., Kaufman, Gregory P., Mavis, Cory, Czuczman, Myron S, Hernand ez-Ilizaliturri, Francisco J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355050/ https://www.ncbi.nlm.nih.gov/pubmed/28055975 http://dx.doi.org/10.18632/oncotarget.14405

Ejemplares similares

Up-regulation of hexokinase II contributes to rituximab-chemotherapy resistance and is a clinically relevant target for therapeutic development
por: Gu, Juan J., et al.
Publicado: (2017)

The adhesion molecule ICAM-1 in diffuse large B-cell lymphoma post-rituximab era: relationship with prognostic importance and rituximab resistance
por: Liu, Yizhen, et al.
Publicado: (2020)

Mitotic Spindle Disruption by Alternating Electric Fields Leads to Improper Chromosome Segregation and Mitotic Catastrophe in Cancer Cells
por: Giladi, Moshe, et al.
Publicado: (2015)

A link between mitotic defects and mitotic catastrophe: detection and cell fate
por: Sazonova, Elena V., et al.
Publicado: (2021)

Bortezomib Is Effective in the Treatment of T Lymphoblastic Leukaemia by Inducing DNA Damage, WEE1 Downregulation, and Mitotic Catastrophe
por: Din, Rahman Ud, et al.
Publicado: (2023)

Mitotic catastrophe and cell death induced by depletion of centrosomal proteins
por: Kimura, M, et al.
Publicado: (2013)

The effect of paclitaxel on apoptosis, autophagy and mitotic catastrophe in AGS cells
por: Khing, Tin Myo, et al.
Publicado: (2021)

Kanakugiol, a Compound Isolated from Lindera erythrocarpa, Promotes Cell Death by Inducing Mitotic Catastrophe after Cell Cycle Arrest
por: Lee, Jintak, et al.
Publicado: (2020)

A Subpopulation of the K562 Cells Are Killed by Curcumin Treatment after G2/M Arrest and Mitotic Catastrophe
por: Martinez-Castillo, Macario, et al.
Publicado: (2016)

Mitotic catastrophe triggered in human cancer cells by the viral protein apoptin
por: Lanz, H L, et al.
Publicado: (2013)

Polyoma small T antigen triggers cell death via mitotic catastrophe
por: Fernando, Arun T Pores, et al.
Publicado: (2014)

CENPE Inhibition Leads to Mitotic Catastrophe and DNA Damage in Medulloblastoma Cells
por: Iegiani, Giorgia, et al.
Publicado: (2021)

Resveratrol abrogates the Temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the Temozolomide-induced senescence in glioma cells
por: Filippi-Chiela, Eduardo C, et al.
Publicado: (2013)

Caffeine Sensitizes U87-MG Human Glioblastoma Cells to Temozolomide through Mitotic Catastrophe by Impeding G2 Arrest
por: Li, Ning, et al.
Publicado: (2018)

Mitotic arrest affects clustering of tumor cells
por: Bonnet, Julia, et al.
Publicado: (2021)

Delayed cell death associated with mitotic catastrophe in γ-irradiated stem-like glioma cells
por: Firat, Elke, et al.
Publicado: (2011)

Upregulation of meiosis-specific genes in lymphoma cell lines following genotoxic insult and induction of mitotic catastrophe
por: Kalejs, Martins, et al.
Publicado: (2006)

Metformin sensitizes therapeutic agents and improves outcome in pre-clinical and clinical diffuse large B-cell lymphoma
por: Singh, Anil R., et al.
Publicado: (2020)

Retinal pigment epithelial cells undergoing mitotic catastrophe are vulnerable to autophagy inhibition
por: Lee, S Y, et al.
Publicado: (2014)

BI2536 induces mitotic catastrophe and radiosensitization in human oral cancer cells
por: Cheng, Chieh-Yuan, et al.
Publicado: (2018)

Mitotic Catastrophe in BC3H1 Cells following Yessotoxin Exposure
por: Korsnes, Mónica Suárez, et al.
Publicado: (2017)

Abnormal expression of H-Ras induces S-phase arrest and mitotic catastrophe in human T-lymphocyte leukemia
por: Dominguez, Jorge Antonio Zamora, et al.
Publicado: (2023)

Involvement of autophagy in the outcome of mitotic catastrophe
por: Sorokina, Irina V., et al.
Publicado: (2017)

Subamolide A Induces Mitotic Catastrophe Accompanied by Apoptosis in Human Lung Cancer Cells
por: Hung, Jen-Yu, et al.
Publicado: (2013)

Mitotic Catastrophe Induced in HeLa Tumor Cells by Photodynamic Therapy with Methyl-aminolevulinate
por: Mascaraque, Marta, et al.
Publicado: (2019)

Telomere erosion in human pluripotent stem cells leads to ATR-mediated mitotic catastrophe
por: Vessoni, Alexandre T., et al.
Publicado: (2021)

FBH1 deficiency sensitizes cells to WEE1 inhibition by promoting mitotic catastrophe
por: Jennings, Lucy, et al.
Publicado: (2023)

The Multikinase Inhibitor AD80 Induces Mitotic Catastrophe and Autophagy in Pancreatic Cancer Cells
por: Lima, Keli, et al.
Publicado: (2023)

A novel M phase blocker, DCZ3301 enhances the sensitivity of bortezomib in resistant multiple myeloma through DNA damage and mitotic catastrophe
por: Hu, Liangning, et al.
Publicado: (2020)

A phase 2 study of rituximab, bendamustine, bortezomib and dexamethasone for first-line treatment of older patients with mantle cell lymphoma
por: Gressin, Rémy, et al.
Publicado: (2019)

Pevonedistat, a NEDD8‐activating enzyme inhibitor, induces apoptosis and augments efficacy of chemotherapy and small molecule inhibitors in pre‐clinical models of diffuse large B‐cell lymphoma
por: Torka, Pallawi, et al.
Publicado: (2020)

Mitotic Arrest in Teratoma Susceptible Fetal Male Germ Cells
por: Western, Patrick S., et al.
Publicado: (2011)

Targeting regulatory T cells by E7777 enhances CD8 T-cell–mediated anti-tumor activity and extends survival benefit of anti-PD-1 in solid tumor models
por: Mahdi, Haider S., et al.
Publicado: (2023)

Bortezomib/ibrutinib/rituximab: Various toxicities: case report
Publicado: (2021)

Erratum to “Subamolide A Induces Mitotic Catastrophe Accompanied by Apoptosis in Human Lung Cancer Cells”
por: Hung, Jen-Yu, et al.
Publicado: (2013)

Pharmacological inactivation of CHK1 and WEE1 induces mitotic catastrophe in nasopharyngeal carcinoma cells
por: Mak, Joyce P.Y., et al.
Publicado: (2015)

αTAT1 downregulation induces mitotic catastrophe in HeLa and A549 cells
por: Chien, J-Y, et al.
Publicado: (2016)

Aurora A inhibition limits centrosome clustering and promotes mitotic catastrophe in cells with supernumerary centrosomes
por: Navarro-Serer, Bernat, et al.
Publicado: (2019)

Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe
por: Zhang, Guoxin, et al.
Publicado: (2021)

Purging human ovarian cortex of contaminating leukaemic cells by targeting the mitotic catastrophe signalling pathway
por: Eijkenboom, Lotte, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_s2epf5ptchtb6dqkbrckr1p4ru