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Androgen suppresses protein kinase D1 expression through fibroblast growth factor receptor substrate 2 in prostate cancer cells

In prostate cancer, androgen/androgen receptor (AR) and their downstream targets play key roles in all stages of disease progression. The protein kinase D (PKD) family, particularly PKD1, has been implicated in prostate cancer biology. Here, we examined the cross-regulation of PKD1 by androgen signa...

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Detalles Bibliográficos
Autores principales: Zhang, Liyong, Zhao, Zhenlong, Xu, Shuping, Tandon, Manuj, LaValle, Courtney R., Deng, Fan, Wang, Q. Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355056/
https://www.ncbi.nlm.nih.gov/pubmed/28077787
http://dx.doi.org/10.18632/oncotarget.14536