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Reactive oxygen species mediate heat stress-induced apoptosis via ERK dephosphorylation and Bcl-2 ubiquitination in human umbilical vein endothelial cells

Heat stress can induce the mitochondrial apoptotic pathway in HUVEC cells, indicating that apoptosis may be a prominent pathological feature of heat stroke, however, little is known about the precise mechani sms involved in it. In this study, we describe the apoptotic effect of intense heat stress o...

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Detalles Bibliográficos
Autores principales: Li, Li, Tan, Hongping, Yang, Hong, Li, Feng, He, Xuan, Gu, Zhengtao, Zhao, Ming, Su, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355065/
https://www.ncbi.nlm.nih.gov/pubmed/28038454
http://dx.doi.org/10.18632/oncotarget.14186