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Frequent amplification of receptor tyrosine kinase genes in well-differentiated/ dedifferentiated liposarcoma

Well-differentiated liposarcoma (WDLPS) and dedifferentiated liposarcoma (DDLPS) are closely related tumors commonly characterized by MDM2/CDK4 gene amplification, and lack clinically effective treatment options when inoperable. To identify novel therapeutic targets, we performed targeted genomic se...

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Detalles Bibliográficos
Autores principales: Asano, Naofumi, Yoshida, Akihiko, Mitani, Sachiyo, Kobayashi, Eisuke, Shiotani, Bunsyo, Komiyama, Motokiyo, Fujimoto, Hiroyuki, Chuman, Hirokazu, Morioka, Hideo, Matsumoto, Morio, Nakamura, Masaya, Kubo, Takashi, Kato, Mamoru, Kohno, Takashi, Kawai, Akira, Kondo, Tadashi, Ichikawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355068/
https://www.ncbi.nlm.nih.gov/pubmed/28099935
http://dx.doi.org/10.18632/oncotarget.14652