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Frequent amplification of receptor tyrosine kinase genes in well-differentiated/ dedifferentiated liposarcoma
Well-differentiated liposarcoma (WDLPS) and dedifferentiated liposarcoma (DDLPS) are closely related tumors commonly characterized by MDM2/CDK4 gene amplification, and lack clinically effective treatment options when inoperable. To identify novel therapeutic targets, we performed targeted genomic se...
Autores principales: | Asano, Naofumi, Yoshida, Akihiko, Mitani, Sachiyo, Kobayashi, Eisuke, Shiotani, Bunsyo, Komiyama, Motokiyo, Fujimoto, Hiroyuki, Chuman, Hirokazu, Morioka, Hideo, Matsumoto, Morio, Nakamura, Masaya, Kubo, Takashi, Kato, Mamoru, Kohno, Takashi, Kawai, Akira, Kondo, Tadashi, Ichikawa, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355068/ https://www.ncbi.nlm.nih.gov/pubmed/28099935 http://dx.doi.org/10.18632/oncotarget.14652 |
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