miRNA-141 attenuates UV-induced oxidative stress via activating Keap1-Nrf2 signaling in human retinal pigment epithelium cells and retinal ganglion cells

Activation of NF-E2-related factor 2 (Nrf2) signaling could protect cells from ultra violet (UV) radiation. We aim to provoke Nrf2 activation via downregulating its inhibitor Keap1 by microRNA-141 (“miR-141”). In both human retinal pigment epithelium cells (RPEs) and retinal ganglion cells (RGCs), f...

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Detalles Bibliográficos
Autores principales: Cheng, Li-Bo, Li, Ke-ran, Yi, Nan, Li, Xiu-miao, Wang, Feng, Xue, Bo, Pan, Ying-shun, Yao, Jin, Jiang, Qin, Wu, Zhi-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355087/
https://www.ncbi.nlm.nih.gov/pubmed/28061435
http://dx.doi.org/10.18632/oncotarget.14489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355087/
https://www.ncbi.nlm.nih.gov/pubmed/28061435
http://dx.doi.org/10.18632/oncotarget.14489

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