Cargando…

Pyruvate dehydrogenase expression is negatively associated with cell stemness and worse clinical outcome in prostate cancers

Cells generate adenosine-5′-triphosphate (ATP), the major currency for energy-consuming reactions, through mitochondrial oxidative phosphorylation (OXPHOS) and glycolysis. One of the remarkable features of cancer cells is aerobic glycolysis, also known as the “Warburg Effect”, in which cancer cells...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhong, Yali, Li, Xiaoli, Ji, Yasai, Li, Xiaoran, Li, Yaqing, Yu, Dandan, Yuan, Yuan, Liu, Jian, Li, Huixiang, Zhang, Mingzhi, Ji, Zhenyu, Fan, Dandan, Wen, Jianguo, Goscinski, Mariusz Adam, Yuan, Long, Hao, Bin, Nesland, Jahn M, Suo, Zhenhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355102/
https://www.ncbi.nlm.nih.gov/pubmed/28076853
http://dx.doi.org/10.18632/oncotarget.14527