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Integrated proteomic and N-glycoproteomic analyses of doxorubicin sensitive and resistant ovarian cancer cells reveal glycoprotein alteration in protein abundance and glycosylation

Ovarian cancer is one of the most common cancer among women in the world, and chemotherapy remains the principal treatment for patients. However, drug resistance is a major obstacle to the effective treatment of ovarian cancers and the underlying mechanism is not clear. An increased understanding of...

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Detalles Bibliográficos
Autores principales: Ji, Yanlong, Wei, Shasha, Hou, Junjie, Zhang, Chengqian, Xue, Peng, Wang, Jifeng, Chen, Xiulan, Guo, Xiaojing, Yang, Fuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355108/
https://www.ncbi.nlm.nih.gov/pubmed/28077793
http://dx.doi.org/10.18632/oncotarget.14542