Intraperitoneal immunotherapy with T cells stably and transiently expressing anti-EpCAM CAR in xenograft models of peritoneal carcinomatosis

The epithelial cell adhesion molecule (EpCAM) is overexpressed in a wide variety of tumor types, including peritoneal carcinomatosis (PC) from gastrointestinal and gynecological malignancies. To develop a chimeric antigen receptor T (CART) cell therapy approach to treat patients with end-stage PC, w...

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Detalles Bibliográficos
Autores principales: Ang, Wei Xia, Li, Zhendong, Chi, Zhixia, Du, Shou-Hui, Chen, Can, Tay, Johan C.K., Toh, Han Chong, Connolly, John E., Xu, Xue Hu, Wang, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355119/
https://www.ncbi.nlm.nih.gov/pubmed/28088790
http://dx.doi.org/10.18632/oncotarget.14592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355119/
https://www.ncbi.nlm.nih.gov/pubmed/28088790
http://dx.doi.org/10.18632/oncotarget.14592

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