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Intraperitoneal immunotherapy with T cells stably and transiently expressing anti-EpCAM CAR in xenograft models of peritoneal carcinomatosis
The epithelial cell adhesion molecule (EpCAM) is overexpressed in a wide variety of tumor types, including peritoneal carcinomatosis (PC) from gastrointestinal and gynecological malignancies. To develop a chimeric antigen receptor T (CART) cell therapy approach to treat patients with end-stage PC, w...
Autores principales: | Ang, Wei Xia, Li, Zhendong, Chi, Zhixia, Du, Shou-Hui, Chen, Can, Tay, Johan C.K., Toh, Han Chong, Connolly, John E., Xu, Xue Hu, Wang, Shu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355119/ https://www.ncbi.nlm.nih.gov/pubmed/28088790 http://dx.doi.org/10.18632/oncotarget.14592 |
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