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FAK regulates E-cadherin expression via p-Src(Y416)/p-ERK(1/2)/p-Stat3(Y705) and PPAR(γ)/miR-125b/Stat3 signaling pathway in B16F10 melanoma cells
Focal adhesion kinase (FAK) is involved in tumor cell migration and metastasis. However, the underlying mechanism remains unclear. Here, we present a signaling pathway involved in the regulation of melanoma cell migration by FAK. We found that the interference of FAK expression suppressed B16F10 cel...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355148/ https://www.ncbi.nlm.nih.gov/pubmed/28108732 http://dx.doi.org/10.18632/oncotarget.14687 |