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FAK regulates E-cadherin expression via p-Src(Y416)/p-ERK(1/2)/p-Stat3(Y705) and PPAR(γ)/miR-125b/Stat3 signaling pathway in B16F10 melanoma cells

Focal adhesion kinase (FAK) is involved in tumor cell migration and metastasis. However, the underlying mechanism remains unclear. Here, we present a signaling pathway involved in the regulation of melanoma cell migration by FAK. We found that the interference of FAK expression suppressed B16F10 cel...

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Detalles Bibliográficos
Autores principales: Pei, Guoshun, Lan, Yan, Chen, Dianhua, Ji, Lina, Hua, Zi-chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355148/
https://www.ncbi.nlm.nih.gov/pubmed/28108732
http://dx.doi.org/10.18632/oncotarget.14687