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Cell membrane-anchored MUC4 promotes tumorigenicity in epithelial carcinomas

The cell surface membrane-bound mucin protein MUC4 promotes tumorigenicity, aggressive behavior, and poor outcomes in various types of epithelial carcinomas, including pancreatic, breast, colon, ovarian, and prostate cancer. This review summarizes the theories and findings regarding MUC4 function, a...

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Detalles Bibliográficos
Autores principales: Xia, Pengpeng, Choi, Agnes Hakyung, Deng, Zengping, Yang, Yuqian, Zhao, Jing, Wang, Yiting, Hardwidge, Philip R., Zhu, Guoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355169/
https://www.ncbi.nlm.nih.gov/pubmed/27829225
http://dx.doi.org/10.18632/oncotarget.13122