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Full preclinical validation of the 123I-labeled anti-PSMA antibody fragment ScFvD2B for prostate cancer imaging

PURPOSE: In the context of prostate cancer (PCa) imaging, the aim of this study was to optimize (in vitro) the specificity and assess preclinically (in vivo) the tumor targeting properties of the (123)I-scFvD2B antibody specific for prostate-specific membrane antigen (PSMA). EXPERIMENTAL DESIGN: The...

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Detalles Bibliográficos
Autores principales: Frigerio, Barbara, Franssen, Gerben, Luison, Elena, Satta, Alessandro, Seregni, Ettore, Colombatti, Marco, Fracasso, Giulio, Valdagni, Riccardo, Mezzanzanica, Delia, Boerman, Otto, Canevari, Silvana, Figini, Mariangela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355234/
https://www.ncbi.nlm.nih.gov/pubmed/28051996
http://dx.doi.org/10.18632/oncotarget.14229