Cargando…

Modeling the phenotype of spinal muscular atrophy by the direct conversion of human fibroblasts to motor neurons

Spinal muscular atrophy (SMA) is a lethal autosomal recessive neurological disease characterized by selective degeneration of motor neurons in the spinal cord. In recent years, the development of cellular reprogramming technology has provided an alternative and effective method for obtaining patient...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Qi-Jie, Li, Jin-Jing, Lin, Xiang, Lu, Ying-Qian, Guo, Xin-Xin, Dong, En-Lin, Zhao, Miao, He, Jin, Wang, Ning, Chen, Wan-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355236/
https://www.ncbi.nlm.nih.gov/pubmed/28099929
http://dx.doi.org/10.18632/oncotarget.14641