Central spindle proteins and mitotic kinesins are direct transcriptional targets of MuvB, B-MYB and FOXM1 in breast cancer cell lines and are potential targets for therapy

The MuvB multiprotein complex, together with B-MYB and FOXM1 (MMB-FOXM1), plays an essential role in cell cycle progression by regulating the transcription of genes required for mitosis and cytokinesis. In many tumors, B-MYB and FOXM1 are overexpressed as part of the proliferation signature. However...

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Detalles Bibliográficos
Autores principales: Wolter, Patrick, Hanselmann, Steffen, Pattschull, Grit, Schruf, Eva, Gaubatz, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355254/
https://www.ncbi.nlm.nih.gov/pubmed/28061449
http://dx.doi.org/10.18632/oncotarget.14466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355254/
https://www.ncbi.nlm.nih.gov/pubmed/28061449
http://dx.doi.org/10.18632/oncotarget.14466

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