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Keap1/Nrf2 pathway in kidney cancer: frequent methylation of KEAP1 gene promoter in clear renal cell carcinoma

The Keap1/Nrf2 pathway is a master regulator of the cellular redox state through the induction of several antioxidant defence genes implicated in chemotherapeutic drugs resistance of tumor cells. An increasing body of evidence supports a key role for Keap1/Nrf2 pathway in kidney diseases and renal c...

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Detalles Bibliográficos
Autores principales: Fabrizio, Federico Pio, Costantini, Manuela, Copetti, Massimiliano, la Torre, Annamaria, Sparaneo, Angelo, Fontana, Andrea, Poeta, Luana, Gallucci, Michele, Sentinelli, Steno, Graziano, Paolo, Parente, Paola, Pompeo, Vincenzo, Salvo, Laura De, Simone, Giuseppe, Papalia, Rocco, Picardo, Francesco, Balsamo, Teresa, Flammia, Gerardo Paolo, Trombetta, Domenico, Pantalone, Angela, Kok, Klaas, Paranita, Ferronika, Muscarella, Lucia Anna, Fazio, Vito Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355256/
https://www.ncbi.nlm.nih.gov/pubmed/28061437
http://dx.doi.org/10.18632/oncotarget.14492