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Keap1/Nrf2 pathway in kidney cancer: frequent methylation of KEAP1 gene promoter in clear renal cell carcinoma
The Keap1/Nrf2 pathway is a master regulator of the cellular redox state through the induction of several antioxidant defence genes implicated in chemotherapeutic drugs resistance of tumor cells. An increasing body of evidence supports a key role for Keap1/Nrf2 pathway in kidney diseases and renal c...
Autores principales: | Fabrizio, Federico Pio, Costantini, Manuela, Copetti, Massimiliano, la Torre, Annamaria, Sparaneo, Angelo, Fontana, Andrea, Poeta, Luana, Gallucci, Michele, Sentinelli, Steno, Graziano, Paolo, Parente, Paola, Pompeo, Vincenzo, Salvo, Laura De, Simone, Giuseppe, Papalia, Rocco, Picardo, Francesco, Balsamo, Teresa, Flammia, Gerardo Paolo, Trombetta, Domenico, Pantalone, Angela, Kok, Klaas, Paranita, Ferronika, Muscarella, Lucia Anna, Fazio, Vito Michele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355256/ https://www.ncbi.nlm.nih.gov/pubmed/28061437 http://dx.doi.org/10.18632/oncotarget.14492 |
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