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Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells

Glioblastoma (GBM), the most common and aggressive brain tumor in the central nervous system, remains a lethal diagnosis with a median survival of < 15 months. Aberrant expression of the TRPM7 channel has been linked to GBM functions. In this study, using the human GBM cell line U87, we evaluated...

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Detalles Bibliográficos
Autores principales: Wong, Raymond, Turlova, Ekaterina, Feng, Zhong-Ping, Rutka, James T., Sun, Hong-Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355261/
https://www.ncbi.nlm.nih.gov/pubmed/28061441
http://dx.doi.org/10.18632/oncotarget.14496