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MicroRNA-17 is downregulated in esophageal adenocarcinoma cancer stem-like cells and promotes a radioresistant phenotype

Resistance to neoadjuvant chemoradiation therapy (CRT) remains a critical barrier to the effective treatment of esophageal adenocarcinoma (EAC). Cancer stem-like cells (CSCs) are a distinct subpopulation of cells implicated in the resistance of tumors to anti-cancer therapy. However, their role in t...

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Detalles Bibliográficos
Autores principales: Lynam-Lennon, Niamh, Heavey, Susan, Sommerville, Gary, Bibby, Becky A.S., Ffrench, Brendan, Quinn, Jennifer, Gasch, Claudia, O’Leary, John J, Gallagher, Michael F, Reynolds, John V, Maher, Stephen G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355274/
https://www.ncbi.nlm.nih.gov/pubmed/28002789
http://dx.doi.org/10.18632/oncotarget.13940